parasecretion [,pærəsi'kri:ʃən]
- parasecretion的基本解释
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分泌异常, 分泌紊乱
- 更多网络例句与parasecretion相关的网络例句 [注:此内容来源于网络,仅供参考]
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Recombinant hANG had no effect on the expression of VEGF and bFGF in both SMCC-7221 cells and HUVEC cells, suggested that hANG exerted its antiangiogenic role not through the inhibition of the autosecretion and parasecretion of angiogenic stimulatory factors VEGF and bFGF.
重组人血管抑素对SMMC-7721肝癌细胞及HUVEC细胞中两种血管生长刺激因子VEGF和bFGF的表达没有影响,提示血管抑素对肿瘤血管生长的抑制作用不是通过抑制血管生长刺激因子的自分泌和旁分泌来实现的。
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There are four kind of isoforms of endothelin in human and other mammals named ET-1, ET-2, ET-3 and ET-β, which are slightly different in construction and pharmacological effect. In human beings, ET-1 is the dominative subtypes. ET-1 remains in blood at a low level about 5ng per liter on physical state. It is synthesized, stored, released and metabolized locally. The half-life of ET-1 is about 1 hour. ET-1 is the most potent vasoconstrictive factor till now, and it is more functional in vein than in artery. In vascular bed, there are two kind of ET receptors. Type A mainly located in smooth muscle cells, whereas type B in endothelial cells. The latter can stimulate intimal hyperplasia via a parasecretion way and activate some oncogenes such as c-fos and c-myc and then enhance their expression. These alterations result in constriction of blood vessels, thus the SMC steps into proliferate state from silent state.
人及哺乳动物体内有四种结构及药理学性质略有差异的异物体,分别为ET-1、ET-2、ET-3、ET-β,而在人主要是ET-1,在生理条件下,ET-1在血浆中含量较低,约为5ng〓,故ET-1不是一个循环激素,而是局部合成释放,局部起作用的活性物质,半衰期约1小时,ET-1是目前已知的最强的血管收缩剂,对静脉的作用比动脉强,在血管床,ET受体有A、B两型,A型主要分布在平滑肌细胞,B型主要分布在内皮细胞,它可以通过旁分泌途径刺激内膜增生,具有有丝分裂原效应,可以激活某些癌基因如C-fos、C-myc使其表达增强引起血管收缩,使静止期SMC进入增殖期,还可以通过信号传导途径,与bFGF、GTF-β、PDGF等生长因子协同作用,起共有丝分裂原作用。
- 更多网络解释与parasecretion相关的网络解释 [注:此内容来源于网络,仅供参考]
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parasecretion:分泌紊乱
unseemly 不体面的, 不适宜的, 不恰当的 不体面地 | parasecretion 分泌紊乱 | undiscerning 无辨别力的, 迟钝的,无眼力的
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parasecretion:分泌紊乱 分泌异常
parascutellum /侧小盾片/ | parasecretion /分泌紊乱/分泌异常/ | paraselene /幻月/
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parasecretion:分泌异常
parasecretion 分泌紊乱 | parasecretion 分泌异常 | paraselene 幻月