mis-sense

与mis-sense相关的网络例句 [注：此内容来源于网络，仅供参考]

Mis-sense mutation changed aminoacids and space conformation of RASS, whereby affecting functions of the protein.

错义突变导致编码的氨基酸改变，影响RASS蛋白的空间构象，进而影响蛋白质的功能。

The majority of keratin mutations are dominant acting and mostly involve mis-sense or small insertion/deletion mutations clustering at the ends of the rod domain of the keratin molecule.

目前报道的基因突变点集中在角蛋白1A螺旋起始区和2B螺旋末端的高度保守区，基因突变方式多数为错义突变，偶有小片段插入或缺失突变。

A type has 7 point mutations(5 samples). B type has 6 point mutations (3 samples), C type has 4 point mutations (3 samples) and D type has 2 point mutations(1sample). Acid amino alignment shows that the most mutations of gastric cancer are mis-sense mutations, few ones are synonymous mutations. Most of the mutations occurred in regulating domain down to the HMG-box,only 2 sites in HMG-box.The mutations have same sites in middle and late stage samples. The results revealed that SOX4 mutations are associated with gastric cancer,which is possible a late accident in gastric cancer.

通过对相应的氨基酸序列的比对发现，发生在中晚期胃癌中的突变多为错义突变，同义突变不多，且突变大多发生在HMG盒下游编码区，在HMG盒内的突变只有两处，中期胃癌与晚期胃癌的突变有相同之处，但SOX4基因的突变位点随肿瘤的演进有增加的趋势。

与mis-sense相关的网络解释 [注：此内容来源于网络，仅供参考]

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