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They are synthesized from glycerol phosphate and fatty acyl CoAs, usually in the microsomes.
其合成多在微生物中进行,原料为磷酸甘油和脂肪酰辅酶 A 。
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Four detergents above mentioned didn't denature P450 of microsomes in midgut and fatbody at concentration of 0.5%.
在0.5%浓度下,四种去垢剂均未使中肠和脂肪体微粒体P450变性。
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This detoxification system is located in liver microsomes and requires uridine diphosphate glucuronic acid.
这解毒系统位于肝脏微粒体和需要二磷酸尿苷葡萄糖醛酸。
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The above results suggests that the hydrolase and FMO in microsomes are involved in the formation of M1 and M2 respectively.
黄素单氧化酶的特异性抑制剂甲巯咪唑可以显著地抑制M2的形成,但对M1的形成无明显的抑制作用,且M1在肝微粒体中的形成为NADPH非依赖性,上述结果提示参与M1和M2代谢的酶分别为肝微粒体中的水解酶和黄素单氧化酶。
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Aim of this study was to preparation of human and rat liver microsomes and determination of metabolite profile in liver.
本研究的目的是建立体外药物代谢研究用的人和鼠肝微粒体药物代谢模型,并对其应用进行初探。
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liver microsomes:肝微粒体
常见的体外代谢试验采用肝细胞(hepatocytes)、肝切片(liver slices)、肝微粒体(liver microsomes)和组合酶(recombinant enzymes). 这些酶的系统各有其优点和缺点,比如说肝细胞具有完整的细胞结构,比其他系统更能代表体内的代谢,
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liver microsomes:肝脏微粒体
Liquid chromatography 液相层析法 30 | Liver microsomes 肝脏微粒体 118 | Loading capacity 装载量 88