metrazol ['metrəzəul]
- metrazol的基本解释
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n.
强心剂, 精神病的冲疗法用剂, 其商标名
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The administration of sufficient Metrazol to induce convulsions and coma.
服用足够量的卡地阿唑以导致抽搐和昏迷的休克疗法。
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MethodsⅠMaximal electroshock seizure was adopted to analyse the relative of dose and effect, relative of time and effect, including maximal efficacy and potency of these five extractives in mice given by ig administration.ⅡMetrazol seizure test was used to compare seizure latency, anticonvulsant rate and mortality of mice with every extractives.ⅢPharmacodynamic parameters of five alcoholic extractives were assayed by means of Pharmacological Effective Method.ⅣUsing the model of seizure rats induced by penicillin localized injected in cortex,we studied the effect of extractives on seizure latency, frequency of epileptiform discharge, highest wave of hippocampus EEG(Recoded by RM6240C multichannel physiological signal collection and analysis recorde), the changes of convulsant behaviors and the latency of seizure.
方法①采用最大电休克惊厥模型,分析灌胃小鼠各药的量效和时效关系,比较其效价强度和效能;②采用戊四唑惊厥模型,比较ig小鼠各药的惊厥潜伏期、抗惊厥率和死亡率;③采用药效法,运用数学模式及参数来模拟各药在体内的药效动力学过程;④制备大鼠皮层定位注射青霉素点燃模型,采用RM6240C型多道生理信号采集处理系统记录脑电图,比较ig各药对痫性发作潜伏期及发作程度、痫性放电潜伏期、痫波发放频率及最高波幅的影响;⑤采用HPLC法测定海马区癫痫相关递质的含量,比较各药对Glu、Asp、Gly、GABA的影响。
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metrazol:精神病的冲疗法用剂
metrauxe 子宫肥大 | metrazol 精神病的冲疗法用剂 | metrechon 使用于扫描转换器中的储存管
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metrazol:卡地阿唑
metrauxe子宫肥大 | metrazol卡地阿唑 | metrazole环戊并四唑
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metrazol:四氮五甲烷
\\"子宫痛\\",\\"metralgia\\" | \\"四氮五甲烷\\",\\"metrazol\\" | \\"美德佐(强心药)\\",\\"metrazole\\"
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metrazol seizure threshold test:abbr. mstt; 最小电休克