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Objective To study the efficacies of quadruple regimens for thetreatment of peptic ulcer disease and eradication of Helicobacter pylori.Methods 102patients with Hp associated peptic ulcer were randomly divided into three groups,groupA（n=98）received sanjiuweitai-based quadruple regimen（Yangweishul.2g,bid+ranitidine150mg,bid+amoxicillin500mg,bid+metronidazole400mg,bid）;group B（n=31）received colloidal bisˉmuth subcitrate110mg,bid+ranitidine150mg,bid+amoxicillin500mg,bid+metronidazole400mg,bid;groupC（n=23）received ranitidine150mg,bid+amoxicillin500mg,bid+metronidazole400mg,bid.Antibiotics were griven for two weeks,the other drugs were given for six weeks,the efficacies were determined by gastroendoscopy or 13 C—UBT.

目的 探讨四联疗法对消化性溃疡的治疗作用及根除幽门螺杆菌的效果方法将102例胃镜证实消化性溃疡者随机分为3组，A组48例给予养胃舒1.2g+雷尼替丁150mg+阿膜西林500mg+甲硝唑400mg，bid；B组31例给予铋剂220mg+雷尼替丁150mg+阿莫西林500mg+甲硝唑400mg，bid；对照组（C组，23例）给予雷尼替丁150mg+阿莫西林500mg+甲硝唑400mg，bid；以上药物除抗菌药物只服用2周外，其余药物服至6周末疗程结束，第7周复查胃镜和 13 C呼气试验。

Methods 102patients with Hp associated peptic ulcer were randomly divided into three groups,groupA（n=98）received sanjiuweitai-based quadruple regimen（Yangweishul.2g,bid+ranitidine150mg,bid+amoxicillin500mg,bid+metronidazole400mg,bid）;group B（n=31）received colloidal bisˉmuth subcitrate110mg,bid+ranitidine150mg,bid+amoxicillin500mg,bid+metronidazole400mg,bid;groupC（n=23）received ranitidine150mg,bid+amoxicillin500mg,bid+metronidazole400mg,bid.Antibiotics were griven for two weeks,the other drugs were given for six weeks,the efficacies were determined by gastroendoscopy or 13 C—UBT.

将102例胃镜证实为消化性溃疡者随机分为3组，A组48例给予养胃舒1.2g+雷尼替丁150mg+阿膜西林500mg+甲硝唑400mg，bid；B组31例给予铋剂220mg+雷尼替丁150mg+阿莫西林500mg+甲硝唑400mg，bid；对照组（C组，23例）给予雷尼替丁150mg+阿莫西林500mg+甲硝唑400mg，bid；以上药物除抗菌药物只服用2周外，其余药物服至6周末疗程结束，第7周复查胃镜和 13 C呼气试验。

Methods 102patients with Hp associated peptic ulcer were randomly divided into threegroups,groupA（n=98）receivedsanjiuweitai-basedquadrupleregimen（Yangweishul.2g,bid+ranitidine150mg,bid+amoxicillin500mg,bid+metronidazole400mg,bid）;group B（n=31）received colloidal bisˉmuth subcitrate110mg,bid+ranitidine150mg,bid+amoxicillin500mg,bid+metronidazole400mg,bid;groupC（n=23）receivedranitidine150mg,bid+amoxicillin500mg,bid+metronidazole400mg,bid.Antibiotics were griven for two weeks,the other drugs were given for six weeks,the efficacies were determined by gastroendoscopy or 13 C―UBT.

将102例胃镜证实为消化性溃疡者随机分为3组，A组48例给予养胃舒1.2g+雷尼替丁150mg+阿膜西林500mg+甲硝唑400mg，bid；B组31例给予铋剂220mg+雷尼替丁150mg+阿莫西林500mg+甲硝唑400mg，bid；对照组（C组，23例）给予雷尼替丁150mg+阿莫西林500mg+甲硝唑400mg，bid；以上药物除抗菌药物只服用2周外，其余药服至6周末疗程结束，第7周复查胃镜和 13 C呼气试验。

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