leukemia [lju:'ki:miə]

leukemia的基本解释

n.

白血病, 白血球过多症

与leukemia相关的网络例句 [注：此内容来源于网络，仅供参考]

Results among the 104 primary acute leukemia patients, the number of patients with t lymphocyte leukemia,b lymphocyte leukemia,acute myeloblastic leukemia,mixed phenotype acute leukemia and umclassified leukemia were 4(3.8％),38(36.5％),58(55.8％),2(1.9％),and 2(1.9％),respectively.conclusion detecting immune marker on leukemic cell by abc-ap two step immune method is very simple which can be finished with a light microscope,and it can provide a reliable basis for the diagnosis and classification of leukemia and even the targeting therapy for leukemia.

结果 104例初发急性白血病中，t淋巴细胞白血病4例(3.8％)，b淋巴细胞白血病38例(36.5％)，急性髓细胞白血病58例(55.8％)，急性混合性白血病2例(1.9％)，未行明确分类的2例(1.9％)。结论 abc-ap免疫二步法检测白血病细胞免疫标记方法简单，只须普通光学显微镜就能开展实验，可为白血病的诊断、分型、分类乃至白血病靶向治疗提供可靠依据。

Results Among the 104 primary acute leukemia patients, the number of patients with T lymphocyte leukemia,B lymphocyte leukemia,acute myeloblastic leukemia,mixed phenotype acute leukemia and umclassified leukemia were 4(3.8％),38(36.5％),58(55.8％),2(1.9％),and 2(1.9％),respectively.

结果 104例初发急性白血病中，T淋巴细胞白血病4例(3.8％)，B淋巴细胞白血病38例(36.5％)，急性髓细胞白血病58例(55.8％)，急性混合性白血病2例(1.9％)，未行明确分类的2例(1.9％)。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病，不管是急性淋巴性白血病或是急性骨髓性白血病，在染色体11q23部位有染色体易位的情况；这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是，单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%；并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且，这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后，而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖，遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以，白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

与leukemia相关的网络解释 [注：此内容来源于网络，仅供参考]

leukemia：白血病

国家重点基础研究计划首席科学家陈国强在国际上首次报道低氧模拟化合物和低氧环境能够体外诱导白血病细胞分化,并提出低氧诱导因子-1蛋白可能成为筛选诱导分化治疗白血病药物的潜在靶标. 权威刊物美国>(LEUKEMIA)杂志审稿人表示,这一工作可能成为推动白血病治疗学研究的又一重要原创发现.

leukemia：血癌

魁北克验尸官报告,一名长途空中旅客死於所谓经济舱综合症(Economy-Class Syndrome),成为在加国证实的首位因患此.卑诗省的科学家们发现了一种新技术,可以利用干细胞 (Stem Cell) 的爆炸,对血癌 (leukemia) 等疾病进行治疗.

leukemia：白血症

一白血症(leukemia)患者不复发已有两年多,他归功於每日喝甜菜汁和服用脱水肝. 解剖发现90%库西奥科病(Kwashiorkor)死亡者有癌症. (库西奥科病为热带婴幼儿营养缺乏症,原因为低蛋白高糖饮食,临床检查属三级营养不良). 此病多见於中美和南非,

leukemia：(白血球過多症)

对染色体损害的问题 有一研究指出LSD会使染色体发生变态,此种染色体的损害又可变为长期潜伏性的损伤,而导发白血球过多症(Leukemia)或生产畸形婴儿(Defective children)对任何一种药物,在没彻底研究清楚其效力,产生的后果以及副作用之前,

acute leukemia：急性白血病

"急性白血病(acute leukemia)是起源于造血系统干细胞的克隆性恶性疾病骨髓中异常的原始细胞(白血病细胞)大量增殖并浸润各种器官组织正常造血受抑制