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Ketenes, notably dimethyl ketene, readily undergo oligomerization and polymerization
烯酮,特别是二甲基烯酮,很容易齐聚和聚合。
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Because of their strong nucleophility of NHCs, the asymmetric Staudinger reaction between ketenes and imines catalyzed by chiral NHC was achieved, gave -lactams with excellent enantioselectivities.
中文摘要我们组利用氮杂环卡宾的亲核性,成功地实现了氮杂环卡宾催化的烯酮与亚胺的Staudinger反应。
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In the second part of this thesis, a formal [2+2] cycloaddition ketenes and dialkyl azodicarboxylates was studied. We found that by adjusting the substituents in the diazenes, the reaction mode can be completely switched, and furnish four-membered-ring products, aza-b-lactams, the enantioselectivity was up to 91%.
经研究发现,通过对偶氮化合物取代基团的改变,我们可以实现[4+2]环加成反应到[2+2]环加成反应的转变,在手性氮杂环卡宾的作用下,对具有各种取代基的烯酮都可以很好的产率得到氮杂b-内酰胺,其对映选择性最高可以达到91%。
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As open-chain hydroxy aldehydes and hydroxyl ketenes, the monosaccharides are very reactive.
以开链的羟基醛和羟基酮形式存在的单糖非常活泼。
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In the first part of this thesis, a formal [4+2] cycloaddition of ketenes with N-benzoyldiazenes catalyzed by chiral NHCs was studied, which gave 1,3,4-oxadiazin-6-ones in very high yields and enantioselectivites.
论文的第一部分内容是在手性氮杂环卡宾的催化下,烯酮与N-苯甲酰偶氮化合物的环加成反应,合成各种手性的噁二嗪酮,它们还可以经过简单的两步一锅法制备手性氨基酯。
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