isobutyryl [,aisəu'bjutiril]
- isobutyryl的基本解释
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异丁酰
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A process for preparingp-fluo-2-(2-methyl-3-propionyl)-4-oxy-N,3-diphenyl-phenylbutylamide includes such steps as Friedle-Craft acylating of newly prepared phenylacetyl chloride and fluorobenzene under catalysis of AlCl3 to obtain 4-fluoro-phenylbenzyl ketone, brominating at carbonyl alpha position under catalysis of less AlCl3 to obtain alpha-bromo-4-fluo-phenylbenzyl ketone, and condensing with isobutyryl acetanilide under action of sodium ethoxide.
本发明涉及一种制备对氟-2-(2-甲基-3-氧丙基)-4-氧-N,3-二苯基-苯丁酰胺(1)的方法,其包括以下步骤:新制的苯乙酰氯与氟苯在AlCl3催化下进行Friedle-Craft酰化反应,得到对4-氟-苯基苄基酮(4);化合物(4)在少量AlCl3催化下进行羰基α位溴化,得到α-溴-4-氟-苯基苄基酮(5);然后(3)异丁酰乙酰苯胺在乙醇钠作用下与化合物(5)进行缩合。
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The acyl derivatives all exhibited higher inhibitory effect than prinsepiol, among which isobutyryl and diacetate derivatives exhibited highest activity with EC50 of 3.85 mg/L and 5.60 mg/L respectively.
在Prinsepiol 4,4'位引入不同酰基后化合物的抑菌活性均有不同程度提高,其中4,4'-二异丁酰基衍生物和4,4'-二乙酰基衍生物的抑菌活性均较好,有效中浓度(EC50)分别为3.85和5.60 mg/L,是Prinsepiol的6~8倍。
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isobutyryl:异丁酰
shoplift vt, vi. 从商店中偷商品 | isobutyryl 异丁酰 | accelerating space 加速空间
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isobutyryl:异丁酰基
次异丁基 isobutylidyne | 异丁酰基 isobutyryl | 异氰酸基 isocyanato
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isobutyryl chloride:异丁酰氯
isobutyric acid 异丁酸 | isobutyryl chloride 异丁酰氯 | isocaloric ration 等能量日粮
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isobutyryl chloride:氯化異丁烯
260 碘丁烷 Iodobutane | 261 氯化異丁烯 Isobutyryl chloride | 262 甲基丙烯醛 Methacrylaldehyde
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isobutyryl bromide:异丁酰溴
苯异丁酮;异丁酰苯 isobutyrophenone; isobutyrylbenzene | 异丁酰溴 isobutyryl bromide | 过氧化异丁酰基 isobutyryl peroxide
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