intumesced
- intumesced的基本解释
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[变形] intumesce的过去分词
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vi.
肿大, 膨胀
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2Myocardial ultrastructure was normal in the control group,myoneme arranged disordered,the structure of typical sarcomere disappeared, mitochondrium intumesced,interstitial substance fiber hyperplasy,capillary vessel endothelial cell swelled in DG group.Myocardial ultrastructure improved slightly in rats of SM and LM groups. 3NF-κB p65 and COX-2 had a small quantity to present in the myocardium tissue of control group,while the quantity increased obviously in the diabetic group.The level of it in the group of treatment was significant lower than that in the diabetic group.There was significant difference between the two groups. Conclusion Metformin can protect against the heart injury in diabetic.
结果 1与对照组比较,DG组体重明显减轻,血糖、心脏质量指数、INS、TG、T-CH及FFA明显升高(P<0.01);应用 MT治疗后体重无明显增加,INS有所下降,心脏质量指数、血糖、TG及FFA明显降低(P<0.01);DG组心肌组织MDA明显升高,SOD明显降低(P<0.01),MT治疗后上述指标明显改善;2超微结构观察单纯糖尿病组肌丝结构明显紊乱,典型肌小节结构消失,线粒体肿胀、间质纤维增生,微血管内皮细胞肿胀等表现,而SM及LM组可见组织结构有所改善;3对照组心肌NF-κB p65及COX-2只有少量表达,单纯糖尿病组表达量明显增多(P<0.01),MT治疗后表达量明显减少(P<0.01)。