intraduodenal
- intraduodenal的基本解释
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[医] 十二指肠内的
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MethodsThe antipyretic activity of ***PS was observed in rats with high temperature induced by dried yeast and 2,4-dinitrophenol; biliary duct cannula bile at 0.5,1,1.5,2,2.5 h after intraduodenal administration in rats was collected and counted to observe the effect of ***PS on biliary secretion;the weight of cholecyst in mice was counted to observe the effect of ***PS on the cholecyst of mice;the acute toxicity test of ***PS was done with mice.
方法采用干酵母、2,4二硝基苯酚致大鼠发热的模型观察玉米须多糖的解热作用;采用胆管引流法分别收集并计量给药后0.5,1,1.5,2 ,2.5 h的胆汁的方法观察***PS对肝脏分泌胆汁的影响;采用测定小鼠胆囊重量的方法观察***PS对胆囊的影响;对***PS进行了小鼠急性毒性实验。
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It was observed that, at the doses of 50 mg/kg and 100 mg/kg, geniposide could significantly increase the biliary secretion after intraduodenal administration, while crocins showed no effect.
结果显示西红花苷50和100 mg/kg剂量均不增加大鼠的胆汁流量,而京尼平苷50和100 mg/kg剂量均可显著增加大鼠胆汁流量,降低胆汁内胆固醇含量,增加胆汁内HCO-3浓度,但对胆汁酸,胆红素,〔Ca2+〕含量无显著影响。
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Aim To investigate the pharmacokinetics of rabeprazole after intravenous, intraportal and intraduodenal administration at various doses and to clarify the impact of hepatic and intestinal first-pass effects to bioavailability of rabbits.
目的 研究雷贝拉唑在大白兔体内经十二指肠、门静脉与外周静脉等不同方式及不同剂量给药时的药代动力学,并探讨肠道、肝脏首过效应分别对其生物利用度的影响。
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Methods The antipyretic activity of SMPS was observed in rats with high temperature induced by dried yeast and 2,4-dinitrophenol; biliary duct cannula bile at 0.5,1,1.5,2,2.5 h after intraduodenal administration in rats was collected and counted to observe the effect of SMPS on biliary secretion;the weight of cholecyst in mice was counted to observe the effect of SMPS on the cholecyst of mice;the acute toxicity test of SMPS was done with mice.
采用干酵母、2,4二硝基苯酚致大鼠发热的模型观察玉米须多糖的解热作用;采用胆管引流法分别收集并计量给药后0.5,1,1.5,2 ,2.5 h的胆汁的方法观察SMPS对肝脏分泌胆汁的影响;采用测定小鼠胆囊重量的方法观察SMPS对胆囊的影响;对SMPS进行了小鼠急性毒性实验。
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MethodsThe antipyretic activity of SMPS was observed in rats with high temperature induced by dried yeast and 2,4-dinitrophenol; biliary duct cannula bile at 0.5,1,1.5,2,2.5 h after intraduodenal administration in rats was collected and counted to observe the effect of SMPS on biliary secretion;the weight of cholecyst in mice was counted to observe the effect of SMPS on the cholecyst of mice;the acute toxicity test of SMPS was done with mice.
目的研究玉米须多糖的清热利胆作用及急性毒性。方法采用干酵母、2,4二硝基苯酚致大鼠发热的模型观察玉米须多糖的解热作用;采用胆管引流法分别收集并计量给药后0.5,1,1.5,2 ,2.5 h的胆汁的方法观察SMPS对肝脏分泌胆汁的影响;采用测定小鼠胆囊重量的方法观察SMPS对胆囊的影响;对SMPS进行了小鼠急性毒性实验。
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intraduodenal:十二指肠内的
intradex右旋糖酐 | intraduodenal十二指肠内的 | intragenic suppression基因内抑制