incompatibility between two drugs
- incompatibility between two drugs的基本解释
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- 更多 网络例句 与incompatibility between two drugs相关的网络例句 [注:此内容来源于网络,仅供参考]
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In clinical. acetylcholinesterase inhibitors reduce the breakdown of synaptic acetylcholine, have been modestly effective in improving the cognitive deficits of Alzheimer's disease.The goal of this work is to determine enzyme kinetics and mechanisms of acetylcholinesterase and butyrlcholinesterase inhibition by five cardiovascular drugs, lovastatin, simvastatin, amlodipine besylate, nifedipine, and hydralazine hydrochloride, and two benzodiazepines, diazepam and chlordiazepoxide hydrochloride. All drugs in this study are reversible mixed-type inhibitors of acetylcholinesterase and butyrylcholinesterase. The pKi values for acetylcholinesterase and butyrylcholinesterase inhibition by the cardiovascular drugs are linearly correlated with the molecular weights of the drugs with the slopes of 0.005 and 0.0021, respectively. Therefore, van der Waals' interactions between acetylcholinesterase and the cardiovascular drugs are stronger than those between butyrylcholinesterase and the drugs. This is probably due to a smaller active site gorge and a more significant peripheral anionic substrate binding site of acetylcholinesterase than those of butyrylcholinesterase.
本研究之目的系决定乙醯胆碱酯酵素和丁醯胆碱酯酵素被五种心脏血管药物lovastatin, simvastatin, amlodipine besylate, nifedipine、hydralazine hydrochloride和两种benzodiazepines:diazepam和Chlordiazepoxide hydrochloride的抑制作用之动力学及机转,这些药物都是乙醯胆碱酯酵素和丁醯胆碱酯酵素的可逆性、混合型之抑制剂,实验结果显示,五种心血管药物对於乙醯胆碱酯酵素及丁醯胆碱酯酵素抑制之pKi值和药物之分子量呈直线之关系,斜率分别为0.005及0.0021因此丁醯胆碱酯酵素,与心血管药物间之凡德瓦作用(van der Waals' )比乙醯胆碱酯酵素与心血管药物间者弱,这可能原因是丁醯胆碱酯酵素之活性区域比乙醯胆碱酯酵素之活性区域更宽广,但丁醯胆碱酯酵素之周边阴离子区域不及乙醯胆碱酯酵素之周边阴离子区域者明显重要,由於五种心血管药物对於乙醯胆碱酯酵素和丁醯胆碱酯酵素抑制之pKi值存在著线性关系表示此种抑制作用系经过共同之反应机理。
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The article 353rd first section second section as well as article 354th of Chinese new penal code fascicle 1997 emendation fascicule, stipulate separately that crime of taking drugs by Tempting, inciting, cheating the others; crime of taking drugs by forcing the others as well as tolerating other people to take drugs, these three accusation are all around the implement which revolving other people in the objective aspect to take drugs or be injected narcotics. The author calls it crime of taking drugs in this paper for the three kinds crime of luring other people to take drugs or the drug-injection for others.
我国1997年修订后的新刑法典分则第三百五十三条第一款、第二款、第三百五十四条分别规定了引诱教唆、欺骗他人吸毒罪、强迫他人吸毒罪和容留他人吸毒罪,这三个罪名在客观方面都是围绕他人吸食、注射毒品而实施的,笔者在本文中把这三种针对他人吸食、注射毒品的犯罪称之为吸毒型犯罪。
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Pharmaceutical excipients were used as a vehicle of water-soluble, liposoluble and even indissolvable drugs with low toxicity and satisfactory biocompatibility. Furthermore, it provides direction and method to decrease efflux of cytotoxic drugs from the cancer cells, promote the effect of clinical therapeutic efficacy, recover the sensitivity of the cancer cells to the cytotoxic drugs, and improve the characteristics of pharmacokinetics of some drugs such as increasing the absorption of some orally drugs, decreasing the renal clearance and hepat-clearance.
此外,通过抑制P-gp的外排功能,一些药用辅料具有逆转肿瘤细胞多药耐药的作用,为临床提高抗肿瘤药物的疗效,减少肿瘤细胞对药物的外排,提高其对药物的敏感性,提供了研究方向和试验手段。
- 更多网络解释 与incompatibility between two drugs相关的网络解释 [注:此内容来源于网络,仅供参考]
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Nonprescription:非處方藥 非处方药
drugs, traditional 傳統藥 传统药 | drugs,nonprescription;over the counter drugs; OTC drugs 非處方藥 非处方药 | drugs; medicine; pharmaceuticals 藥品 药品
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gametophytic self-incompatibility system:配子体自交不亲和系统
细胞质不亲和性 cytoplasmic incompatibility | 配子体自交不亲和系统 gametophytic self-incompatibility system | 孢子体自交不亲和系统 sporophytic self-incompatibility system
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chaulmoogra:大风子
抗微生物药(antimicrobial drugs)是用于治疗病原微生物感染性疾病的药物,能抑制或杀灭病原微生物,包括抗菌药(antibacterial drugs),抗真菌药(antifungal drugs)和抗病毒药(antiviral drugs).对病古印度人用大风子(chaulmoogra)治疗麻风病,我国早有用豆腐霉治疗疖,