griseofulvin [,grizi:əu'fulvin]
- griseofulvin的基本解释
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n.
[微]灰黄霉素
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Drugs (methimazole, methylthiouracil, propylthiouracil and thiouracil); some sedatives (doxylamine succinate and phenobarbital); and some other drugs including the systemic antifungal antibiotic griseofulvin, the diuretic spironolactone, and the antibacterial sulfa drugs sulfamethazine and sulfamethoxazole.
抗甲状腺?药物(他巴唑,甲基硫氧嘧啶,丙基硫氧和硫氧嘧啶);一些镇静剂(doxylamine琥珀和苯巴比妥),以及包括系统性真菌抗生素灰黄霉素,安体舒通的利尿一些其他药物,以及抗菌磺胺类药物和磺胺二甲嘧啶。
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The experimental results show that the mean particle size of griseofulvin precipitated by RESS is smaller than 1, 0μm, narrow distribution and 95% fine particles is smaller than 1. 0μm. Increase of the pre-expansion pressure, the extraction temperature, the expansion chamber temperature, the spraying distance, the concentration of cosolvent and decrease of the nozzle diameter resulted in decrease of the particle size under the operating condition studied. Enhancement of the pre-expansion temperature resulted in increase of the particles size. The SEM of GF shows that the shape of original is atactic and a wide size distribution, but the microparticles obtained by RESS is reverse. Similar melting points and XRD patterns were observed for the original material and the precipitates obtained by RESS.
实验结果表明,用含夹带剂的RESS法制备的灰黄霉素微粒的平均直径在1μm左右,且分布均匀,95%微粒在1μm以下,仅用CO〓作为超临界流体制备的微粒与上述方法制备的微粒的平均直径和分布相似,只是产量太低,而用机械法制备的微粒平均直径在3μm左右且分布较宽;不同的过程参数对沉析微粒尺寸有不同的影响,预膨胀压力、膨胀室温度、溶解温度以及夹带剂浓度的提高或增大,均可使沉析微粒的直径变小;预膨胀温度提高,所得微粒的直径变大;喷射距离的增加,沉析微粒的直径变小;喷嘴直径越小,由此制得的微粒的直径就越小;根据实验结果还可知道,通过理论计算的马赫盘处微粒的直径可以较好地估计出膨胀室中收集到的微粒的直径。
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The ultrasonic extraction process of griseofulvin is feasible, and could be used in routine operation.
本实验所得工艺条件可行,具有一定的实际应用价值。
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The most commonly used drug is called griseofulvin, and you usually have to take it for up to 10 weeks.
最常用的药物是所谓的灰黄霉素,你通常都采取它长达10个星期。
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ABSTRACT Objective To study the optimal extraction conditions of griseofulvin by ultrasonic extraction methods.
目的 探讨超声波提取灰黄霉素的优化工艺条件。
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griseofulvin:灰黄霉素
灰黄霉素(griseofulvin)是非多烯类抗真菌抗生素,临床用于头癣、迭瓦癣、皮肤癣等体 表真菌感染,此外还广泛用于森林、牧场的大面积灭菌. 灰黄霉素是我公司抗生素发酵生产 的主要规模产品之一,近几年发酵规模不断扩大,发酵车间也增多.
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griseofulvin:灰黄霉(霉) 素
Grey matter 灰质 | Grid 格子 | Griseofulvin 灰黄霉(霉) 素
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griseofulvin:灰黄霉素[抗生素类药]
Grepafloxacin 格帕沙星[抗菌药] | Griseofulvin 灰黄霉素[抗生素类药] | Guabenxan 胍苯克生[抗高血压药]
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griseofulvin:英文名
英文名:Griseofulvin | 格拉司琼杂质B Granisetron impurity B | 格拉司琼杂质E Granisetron impurity E
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griseofulvin tablet:灰黄霉素片
griseille yarn 织制黑白提花绸的丝线 | griseofulvin tablet 灰黄霉素片 | griseofulvin 灰黄霉素
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