granulation tumor
- granulation tumor的基本解释
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[医] 肉芽肿, 肉芽瘤
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It also is related to bone marrow structural damage resulting from tumor invasion,large proliferation of granulation or fibrous tissue,which often affect hemopoiesis.Leukemoid reaction occurred in the majority of malignancies is myeloid leukemia response,among which some are.neutropenia,and even agranulocytosis and increasion or decreasion of platelets.These are all have close relationship with marrow invasion of malignant tumor,immune reaction of the body and chemotherapy as well as radiotherapy.
亦与骨髓被恶性肿瘤细胞浸润、肉芽和纤维组织大量增生,使骨髓结构破坏,影响红系造血有关;绝大多数恶性肿瘤并发的类白血病反应是粒细胞性的,部分患者白细胞减少,甚至粒细胞缺乏,以及血小板增高或减少,均与恶性肿瘤细胞骨髓浸润、机体的免疫反应、放化疗有关。
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Methods Nuclear β-catenin expression was detected by immunohistochemistry in 77 lesions with desmoid-type fibromatosis and 171 other spindle cell lesions, including superficial fibrmoatosis (n=18), nodular fasciitis (n=36), keloid (n=16), scar (n=10), granulation tissue (n=9), synovial sarcoma (n=38), neufibroma (n=13), solitary fibrous tumor (n=12), gastrointestinal stromal tumor (n=10), low-grade myxofibrosarcoma (n=3), low-grade fibromyxoid sarcoma (n=3), and smooth muscle tumor (n=10). In addition, the immunohistochemical expressions of ER-α, ER-β and Ki-67 were examined in all of the lesions with desmoid-type fibromatosis. The nuclear immunohistochemical staining for nuclear βcatenin and ER-β was graded as high level (≥25% of cells), low level (5%-25%) or none.
采用免疫组织化学染色法检测77例韧带样型纤维瘤病和171例其它良、恶性梭形细胞病变(包括结节性筋膜炎36例、浅部纤维瘤病11例、瘢痕疙瘩16例、增生性瘢痕10例、肉芽组织9例、滑膜肉瘤38例、神经纤维瘤13例、孤立性纤维性肿瘤12例、胃肠间质肿瘤10例、低度恶性黏液纤维肉瘤3例、低度恶性纤维黏液样肉瘤3例及平滑肌肿瘤10例)组织中β-catenin核阳性的表达,同时检测韧带样型纤维瘤病中ER-α、ER-β和Ki-67的表达。
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Granule formation; Hyperplasia of granulation tissue:颗粒层增殖
Granulation tumor 肉芽肿; 肉芽瘤 | Granule formation; Hyperplasia of granulation tissue 颗粒层增殖 | Granulous sarcoid 肉芽肿性类肉瘤