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Methods Seventy-two male Sprague-Dawley rats were randomly divided into three groups: PAN model group, 1,252D3 treated group(T, 0.2 μg·kg-1·d-1 by gavages) and normal control group.
72只雄性SD大鼠随机分为健康对照组、PAN组和1,252D3治疗组 [1,252D3 0.2 μg·kg-1·d-1灌胃]。
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Rats had been oral gavages for ninety days,RT-PCR was applied to detect the expression of BMP-7 mRNA in femoral bone.
结果 醋酸泼尼松致肾阳虚大鼠股骨BMP-7 mRNA和BMP-7的表达明显下降(P<0.05),淫羊藿能在mRNA水平(P<0.05)和蛋白水平上提高股骨BMP-7的表达。
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METHODS Twenty-four App transgenic mice were randomized into three groups: the control group, polygonatum polysaccharide treated group and Vitamin E treated group, and were administered with water for injection, polygonatum polysaccharide solution and Vitamin E solution respectively by gavages for six weeks.
24只App转基因小鼠随机分为对照组、黄精多糖治疗组和维生素E治疗组。各组分别予以注射用水、黄精多糖溶液和维生素E溶液1 mL灌胃,连续6 wk。
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Furthermore, repetitive gavages of MT prevented Phe-induced oxidative injuries, depletion of GSH, decrease of activities of antioxidative enzymes and total antioxidative capacity.
妊娠期MT处理减少正常胎鼠脑中H2O2及产率;同时MT和Phe共同处理可阻断Phe诱发的氧化性损伤,GSH耗竭和抗氧化酶活性的下降。
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Results of acute treatments of oral glucose tolerance test showed that the plasma glucose levels of the diabetic Wistar rats administered, both of guava fruit water or alcohol extracts, with 200 or 400 mg/kg BW were lower than the control group (fed with equal volume of saline solution) after 30 minutes gavages. It is considered that the extracts containing protein, lipid and diet fiber may defer the stomach and small intestines to get empty and interfere or delay the sugar absorption and then increase the glucose utilization in diabetic rats.
结果显示糖尿病鼠不论灌食番石榴果实之水及乙醇萃取物粗萃物200或400 mg/kg BW的剂量,於OGTT第30分钟后的血浆葡萄糖值均比糖尿病控制组显著降低,推测原因可能与番石榴粗萃物所含的蛋白质,脂肪及膳食纤维延缓胃和小肠的排空,具有干扰或减缓葡萄糖的吸收,因而促进体内组织细胞对血液中葡萄糖的利用有关。
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