filterable virus
- filterable virus的基本解释
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n.
滤过性病毒
- 相似词
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Abstract] objective for the purpose of scientific evaluation and improvement on unreasonable parameter of viral inactivation,the dynamics curve of time corresponding to effect by given viral inactivation factor treated to blood plasma product were analyzed.methods aimed at vesicular stomatitis virus, sindbis virus, human immunodeficiency virus, polioviruses, pseudorabies virus,encephalon-yocarditis virus; validate data of viral inactivated on pasteurization of albumin, human rabies immunoglobulin with ph 4, human immunoglobulin and human hepatitis b immunoglobulin for intravenous injection with ph 4/pasteurization,treatment on human fibrinogen and human coagulation factor ⅷ with solvent/detergent and vapor heating at 100 ℃30 min were systemic regularized respectively.the mean and standard deviation also coefficient of variation for virus survival titer in different time were stated, dynamics curve of virus inactivation were made and analyzed.results human albumin pasteurization inactivated vsv and sindbis virus,hrig low ph inactivated vsv and sindbis virus,hrig low ph inactivated hiv virus,ivig low ph/pasteurization inactivated hiv virus,ivig low ph inactivated hiv virus,hbig low ph/pasteurization inactivated vsv,sindbis and polio virus.conclusion suggestion about improvement on unreasonable parameter and standard of virus inactivation is made,cultivate target virus directly from final product by appropriate cell or method to monitoring viral safety of blood plasma product is advanced.
目的 分析血液制品特定灭活因子的时效动力学曲线,科学性地评价与改进不合理的病毒灭活参数。方法系统性整理针对水疱性口炎病毒、黄热病毒、脊髓灰质炎病毒、伪狂犬病毒、脑心肌炎病毒、人类免疫缺陷病毒,人血白蛋白采用巴氏消毒法,狂犬病人免疫球蛋白采用低ph常温孵放法,静注人免疫球蛋白、静注人乙肝免疫球蛋白采用低ph/巴氏消毒法;人纤维蛋白原、人凝血因子ⅷ采用有机溶剂/去污剂与干热法灭活病毒的验证资料,统计3批样品多个取样点的残余病毒滴度均值、标准差与变异系数,制作灭活病毒动力曲线图并进行分析。结果人血白蛋白巴氏灭活vsv与sindbis病毒,hrig低ph灭活vsv和sindbis病毒,hrig低ph灭活hiv病毒,ivig低ph/巴氏灭活hiv病毒,ivig低ph灭活hiv病毒,hbig低ph/巴氏灭活vsv、sindbis与polio病毒。结论建议改进病毒灭活验证标准与不合理的灭活参数;采用终产品样品通过合适细胞或方法直接培养目标病毒来有效监测血液制品的病毒安全性。
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According to the harm degree after virus erupts and consequence, the poison of 10 a serious illness 2007 is ordinal for: U dish virus of verminosis poison, ARP, net swims virus of great robber virus, MSN sexy album, ANI virus, machine dog virus, acting trojan virus, AV killer virus, Real script virus and virus of panda burn joss sticks.
根据病毒爆发后的危害程度和影响力,2007年的十大病毒依次为:U盘寄生虫病毒、ARP病毒、网游大盗病毒、MSN性感相册病毒、ANI病毒、机器狗病毒、代理木马病毒、AV杀手病毒、Real脚本病毒和熊猫烧香病毒。
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Neutralizing potency of the patent recombinant anti-rabies virus McAbs, SO57 and SOJB,have been investigated broadly to different rabies virus strains in various animal models.100% Chinese Hamsters could be protected by 100IU/kg SO57 against China prevalent street rabies virus named SBD.We firstly established the mouse model to simulate human postexposure prophylaxis by rabies virus and found SO57 had the same function with HRIG against CVS or three China typical street rabies viruses.However,HRIG could not 100% protect the mice challenged with SBD street virus,rabies virus vaccine alone could not save life from rabies virus infection.The cocktail containing SOJB and SO57(1:1) did not do better than SO57 alone.
用不同的动物模型研究了具有专利的重组人抗狂犬病病毒单克隆抗体SO57、SOJB对不同狂犬病病毒株的中和作用,100IU/kg的SO57能100%保护被中国街毒株SBD攻击的中国仓鼠;首次用小鼠模型模拟人体被狂犬病病毒攻击后的治疗情况,在小鼠被CVS及中国街毒代表株攻击后,SO57与HRIG具有相近的对小鼠的暴露后保护作用;同时结果显示HRIG对SBD株攻击的保护率不能到达100%,仅使用疫苗是不能对感染病毒的小鼠百分之百的保护;SOJB与SO57 1:1联合使用未显示比SO57单独使用更好的保护效果。
- 更多网络解释 与filterable virus相关的网络解释 [注:此内容来源于网络,仅供参考]
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filterable virus:滤过性病毒
Filter过滤器 | Filterable virus滤过性病毒 | Fimbriae菌毛
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filterable virus:可滤性病毒
filter passing virus 可滤性病毒 | filterable virus 可滤性病毒 | filth fly 家蝇
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filterable virus:滤过性病毒,过滤性病毒
filterable stage 滤过阶段 | filterable virus 滤过性病毒,过滤性病毒 | filtered accumulation 筛选累加
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filterable virus:滤过
filter 过滤器 | filter-tipped 有过滤嘴的 | filterable virus 滤过