exampled

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The 4th left rib was cut and a model of left coronary artery occlusion/release was carried outo Rats were divided randomly into 4 groups: control group without LCA occlusion (group A, n=6);I/R group(group B, n=6); ketamine(5mg.kg-1)+I/R group (group C, n=6); ketamine(10mg.kg-1)+I/R group(group D,n=6)o All rats in groups B, C , D were subjected to 30 minutes of LCA occlusion followed by 120minutes of reperfusion. Rats in group C and D were injected with 5mg.kg-1 and 10mg.kg-1 of ketamine before reperfusion, respectively. Significant electrocardiogram and color changes at the area at risk were considered indicative of successful coronary occlusion and reperfusionc Serum was exampled from left jugular vein at 30 minutes and 120 minutes during reperfusion to measure IL-6 and TNF- level by ELISA measurements. After reperfusion of 120 minutes, the heart was removed and the cardiac apex was exampled with snap-frozen in liquid nitrogen and stored at -70 C .

采用左冠状动脉前降支结扎开放建立心肌缺血／再灌注模型，健康SD大鼠24只，随机分为心包打开假手术组(A组，n=6)，缺血／再灌注对照组(B组，n=6)，5 mg·kg~(-1)氯胺酮+缺血／再灌注组C组，n=6，缺血30min后右腹股静脉注入5 mg·kg~(-1氯胺酮，10mg·kg~(-1)KTM+I／R组D组，n=6，缺血30min后右腹股静脉注入10 mg·kg~(-1氯胺酮。10％水合氯醛40 mg·kg~(-1)腹腔注射麻醉，气管切开，连接多功能监护仪记录心电图；小动物呼吸机人工呼吸，呼吸频率60次／分，潮气量2ml／100g，于左胸第四肋间打开胸腔暴露心脏，在左心耳下1mm左冠状动脉处，用丝线，眼科外用不锈钢小圆针穿过心肌浅层，稳定10min后将U型含有铜丝的胶管置于冠状动脉表面一起结扎(A组不结扎，B、C、D组结扎)；结扎开始左心室心尖部即由红色变暗，30 min后呈暗红色，心电图中出现S-T段抬高，说明缺血形成。

In order to solve some teaching problems of advanced mathematics, the authors of this paper advance whole teaching design, and attempt to expound it s principium with characteristics of mathematics and leaning mentality, then, calculous and part problems are exampled to explain the whole teaching design of advanced mathematics.

为解决高等数学教学存在的问题提出整体教学设计，从数学本身的特点和学生数学学习心理的角度阐述整体教学设计的原理，并以微积分和局部问题为例说明高等数学的整体教学设计。

Aging mechanism of wood-plastic composite was: light and heat break down the long molecular chains of wood flour and plastic; the free radicals reacted with the oxygen, which generated carbonyl groups, hydroperoxides and so on; the free radicals also had cross linking reaction, which generated alkoxy; Water destroyed the interface of wood flour and plastic, hydrolyzed ester additives, extracted the small molecule additives and degradation products; Microorganism degraded cellulose, semicellulose, lignin and ester additives; degradation product from different component accelerated the aging, which could be exampled by the fact that HCl from degradation of PVC accelerated the hydrolyzation of cellulose and semicellulose.

木塑复合材料的老化机理为：光和热引发木塑复合材料中木质组分和塑料组分大分子链断裂，产生的自由基与氧气作用，发生链支化反应生成羰基、氢过氧化物等，发生交联反应生成烷氧基等；水分破坏木-塑界面、水解酯类添加剂、抽提小分子添加剂和降解产物；微生物分解纤维素、半纤维素、木素和酯类添加剂；木塑复合材料中各组分的降解产物相互促进老化，PVC降解产生的HCl溶于水，促进了纤维素和半纤维素的水解。