daphnetin
- daphnetin的基本解释
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[化] 瑞香素, 7,8-二羟香豆素
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Objective To investigate the therapeutic effect of a combination of artemether and daphnetin against Plasmodium berghei ANKA strain in mice. Methods Groups of P.
目的 研究蒿甲醚与瑞香素伍用对感染伯氏疟原虫ANKA株小鼠的疗效及其联合作用方式。
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Objective To investigate the in vitro antimalarial effect of daphnetin relating to its iron-chelating activity.
目的 研究瑞香素体外抗疟作用与其铁螯合能力的关系。
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The dose-dependent antimalarial activity of daphnetin is related to its iron-chelating activity.
瑞香素的抗疟作用与它的铁螯合能力有关。
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Results In vitro ,daphnetin exhibited potent schizontocidal activity comparable to chloroquine at the dose range of 1~10 μmol/L. In vivo ,50 or 100 mg/kg.d -1 ×4 d daphnetin i.g. and 10,50 or 100 mg/kg.d -1 ×4 d dephnetin i.p. showed antimalarial efficacy comparable to CQ 10 mg/kg.d -1 ×4 d i.g. in mice infected with P. berghei ANKA, evaluated by both the reduction rate of parasitemia on D 4 and the average surviving days in 30 days.
结果 体外试验中瑞香素在 1~ 10 μmol L剂量范围内有明显杀灭裂殖体作用,而体内试验中按D4减虫率与感染鼠在 30d内的平均生存天数评价,5 0或 10 0mg kg 。d- 1 × 4d瑞香素灌胃以及 10 ,5 0或 10 0mg kg.d- 1 × 4d瑞香素腹腔注射给药在伯氏鼠疟原虫ANKA株感染鼠中的抗疟作用与 10mg kg 。d- 1 × 4d氯喹灌胃的疗效相似。
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Results Six compounds were obtained and their structures were identified as phytol, 7-hydroxycalamenene, daphnetin, and daucosterol from the alcohol extract, D-glycero-D-galacto-heptitol and D-erythro-L-galacto-octitol from the water extract.
结果 从其乙醇提取物中分离得到植物醇、7-羟基去氢白菖烯、瑞香内酯、胡萝卜苷;从其水提取物中分离得到两个多元醇类化合物,分别是D-glycero-d-galacto-heptitol、D-erythro-L-galacto-octitol。
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Daphnetin:瑞香素
瑞香素(daphnetin)又称祖师麻甲素,化学学名为7,8-二羟基香豆素. 分子式:C9H6O4 瑞香素具有扩张冠状血管,增加冠脉血流量,减少心肌耗氧量,改善心肌代谢促进心功能恢复,扩张末梢血管以及抗动脉血栓形成和抑制血小板凝集作用.
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Daphnetin:祖师麻甲素,(白)瑞香素, 瑞香内酯
Sodium Danshensu 丹参素钠 | Daphnetin 祖师麻甲素,(白)瑞香素, 瑞香内酯, | Daphnin 祖师麻乙素,(白)瑞香甙
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Daphnetin:瑞香素[血管扩张药]
Dapabutan 达帕布坦[消毒防腐药] | Daphnetin 瑞香素[血管扩张药] | Dapiprazole 达哌唑[抗溃疡病药]
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Daphnetin:瑞香素(祖师麻甲素 )
Dandelion P.E 蒲公英提取物 | Daphnetin 瑞香素(祖师麻甲素 ) | Daphnin 瑞香甙(苷)
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Daphnetin std:祖师麻甲素(瑞香素)
Angiosperm Extract 被子植物酸 具有防止发炎及抗过敏效果 | S10393G 祖师麻甲素(瑞香素) Daphnetin std. | S11Y13G1 尿囊素 Allantoin std.
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