cytotrophoblast [,saitəu'trɔfəblæst]
- cytotrophoblast的基本解释
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n.
[生]细胞滋养层
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On the morphological differentiation,by inducing of fetal calf serum,it wasshown that the cytotrophoblast cells underwent aggregation first,and the adjacentcytoplasm membranes became tightly contacted through desomosomes andcytoskeleton.Then the adjacent cytoplasm membranes disintegrated fragmentallyto form fusion pore-like structure.Finally the multinuclear cells formed and inwhich the intercellular desmosomes disappeared.Immunocytochemical stainingfurther demonstrated that the formation of syncytium was through cell membranefusion rather than the amitosis process.
细胞形态分化的研究结果表明:早孕胎盘来源的细胞滋养层细胞在血清诱导下,首先发生聚集,并通过桥粒和细胞骨架使相邻的细胞膜紧密接触;之后细胞膜发生片段断裂,形成融合孔样结构;细胞间桥粒消失,最终形成多核的合体细胞;免疫细胞化学分析进一步证实合体化是通过细胞膜融合而非无丝分裂(amitosis即细胞核分裂而细胞质不分裂)实现的。
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On the functional differentiation,we found and that the type II ras-GTPaseactivating protein (p100-GAP),which was specifically expressed in humanplacenta,was largely expressed in the highly-differentiated syncytiotrophoblastcells and moderately expressed in the cultured intermediate trophoblast cells.While in the non-differentiated cytotrophoblast cell line-NPC,no expression was observed.Its mRNA and protein expressingcharacterization was in consistent with that of hCGβ,which was one of the mostimportant markers of the trophoblast cell functional differentiation.In addition,the expressing amount of p100-GAP increased with the progressing of pregnancyand the syncytium formation in vitro.
细胞功能分化的研究结果表明:经重组质粒的构建获得特异表达于人胎盘的p100-GAP的cDNA探针后,从蛋白和分子水平证实p100-GAP大量表达于分化程度高的合体滋养层细胞,少量表达于体外培养的中间型滋养层细胞,而非分化的细胞滋养层细胞NPC则不表达,这种表达特性与作为滋养层细胞功能分化重要指标之一的hCGβ高度一致;p100-GAP表达量还随妊娠过程和体外合体化过程而逐渐增加。
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Positive immunostain Fas and FasL was mainly located in the cytoplasm and membrane of syncy-tiotrophoblast and cytotrophoblast.
Fas及FasL在重度子痫前期组胎盘绒毛滋养细胞的表达与新生儿出生体重和胎盘重量均有明显相关性。
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Results:Among 20 placenta tissues of the test group,16 samples were found to have Uu infection to different degrees,which resulted in pathological changes of villous cytotrophoblast and villous middle.
结果:试验组胎盘组织中有16例发现有不同程度的Uu感染现象,并引起绒毛滋养层细胞和绒毛间质发生不同程度的病理改变。
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LMWH might regulate cytotrophoblast invasiveness in vitro by influencing the expression of MMP-2 and TIMP-2 in cytotrophoblastic cells.
低分子量肝素可能直接通过影响绒毛滋养层细胞 MMP-2、TIMP-2的表达进而影响绒毛滋养层细胞的侵袭能力。
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cytotrophoblast:细胞滋养层
包围于植入胚的周围. 称此为合体滋养层(sy- ncytialtrophoblast)或海绵滋养层(spongiotro- phoblast). 相反,而与胚胎直接相邻的一层称为细胞滋养层(cytotrophoblast). 海绵滋养层将成为合胞体,认为它能吸收与其相接腔中的母体组织分解物.
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cytotrophoblast:细胞滋养细胞
trophoblast 滋养细胞 | cytotrophoblast 细胞滋养细胞 | syncytiotrophoblast 合体滋养细胞
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cytotrophoblast:滋养药胞层,滋养药内层
\\"细胞毒性\\",\\"cytotoxicity\\" | \\"滋养药胞层,滋养药内层\\",\\"cytotrophoblast\\" | \\"滋养发生层\\",\\"cytotrophoblastic shell\\"
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cytotrophoblast:滋胚内质
\\"细胞毒素\\",\\"cytotoxin\\" | \\"滋胚内质\\",\\"cytotrophoblast\\" | \\"细胞内寄生原虫\\",\\"cytozoic\\"
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cytotrophoblast shell:细胞滋养层壳
cytotrophoblast cell column 细胞滋养层细胞柱 | cytotrophoblast shell 细胞滋养层壳 | free villus 游离绒毛
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