colon ['kəulən]
- colon的基本解释
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n.
冒号, 结肠, 直肠
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Objective To explore livin, MTA1 and the caspase3 protein expression, their correlation and clinical pathology in colon cancer Methods The expressions of livin, MTA1 and caspase3 protein in 88 cases of colon cancer were detected by immunohistochemistry stainingResults Livin, caspase3 protein and MTA1 positive expression rates in colon cancer tissues were more than those in tissues beside the cancer Furthermore there were obvious relevance between livin protein, MTA1 positive expression rate and degree of histodifferentiation and lymph node metabasis and between caspase3 protein positive expression rate and degree of histodifferentiation of colon cancer Caspase3 protein expression had prominent inverse correlation with the livin expressionConclusions ①Over expression of livin having inhibtion on colon cancer is one of important factors of colon carcinogenesis ②Caspase3 protein expression in colon cancer tissues is inhibited to less and has prominent inverse correlation with livin expression Accordingly, suppressing caspase3 protein activity is one of channels, by which livin promotes colon carcinogenesis ③MTA1 plays the important role in histodifferentiation degree and lymph node metastasis of colon cancer
采用免疫组织化学染色方法检测88例结肠癌组织中Livin,Caspase3 及MTA1的表达情况。结果(1)结肠癌组织中Livin的阳性表达率显著高于癌旁组织,且Livin的表达与结肠癌的组织分化程度及淋巴结转移程度显著相关。(2)结肠癌组织中Caspase3蛋白的阳性表达率显著高于癌旁组织,且Caspase3蛋白的表达与结肠癌的组织分化程度显著相关。(3)结肠癌组织中MTA1的阳性表达率显著高于癌旁组织,且MTA1的表达与结肠癌的组织分化程度及淋巴结转移程度显著相关。(4)Caspase3蛋白的表达又与Livin的表达呈显著负相关。结论(1)Livin在结肠癌组织中过表达,它可能是促进结肠癌发生的重要因素之一。(2)Caspase3蛋白在结肠癌组织中表达被抑制而降低,且与Livin的表达呈负相关。因此,抑制Caspase3蛋白的活性是Livin促进结肠癌发生的途径之一。(3)MTA1对结肠癌的组织分化及淋巴转移发挥重要作用。
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Results Well-resolved, reproducible 2-DE profiles of human colon carcinoma tissues and paired normal tumor-adjacent colon tissues were obtained. For colon carcinoma tissues, a total of (980±28) spots were detected; for paired normal tumor-adjacent colon tissues,(860±45) spots were detected. For normal tumor- adjacent colon tissues, the average deviation of spot position was (10.487±0.11) mm in IEF direction and (0.944±0.12) mm in SDS-PGE direction; for colon carcinoma tissues the average deviation of spot position was (0.654±0.11) mm in IEF direction and (1.20±0.22) mm in SDS-PGE direction. Number of differentially expressed proteins was 72.00±12.34 between colon carcinoma and paired normal tumor-adjacent colon tissues.
结果 建立了结肠癌及正常肠组织的双向凝胶电泳图谱,其中癌旁正常结肠组织和结肠癌组织电泳图谱中平均蛋白质点数分别为860±45和980±28;癌旁正常结肠组织和结肠癌组在IEF方向上的平均偏差分别为(0.487±0.11)mm和(0.654±11)mm,在SDS-PAGE方向上的平均偏差分别为(0.944±0.12)mm和(1.20±0.22)mm,结肠癌与癌旁正常结肠组织的差异表达蛋白质点数为72.00±12.34。
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Results: 72 of 86 cases were ileal-colon type (83.7%), 14 cases were ileal-ileal-colon type (16.3%), which 25 cases lain in ileocecal junction, 17 cases in ascending colon, 14 cases in hepatic flexure of colon, 8 cases in transverse colon, 9 cases in splenic flexure of colon and 5 cases in decending colon.
结果:86例患者中,回-结肠型72例(83.7%),回-回-结肠型14例(16.3%),套头位于回盲部25例,升结肠17例,结肠肝曲14例,横结肠8例,结肠脾曲9例,降结肠5例。81例患者复位成功,成功率约94.2%。
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colon:冒号
含下划线 "_" (underscore) 的讯息多数是选单项目或而对话盒标签,显示时会将随后的字符加上底线,表示可以按 Alt-Key 跳到该项目. 以冒号 ":" (colon) 为尾的讯息多数是对话盒标签,例如:
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colon:结肠
特点 结肠(colon) 观察标本结肠横切片(H.E染色) 肉眼观察肠壁的粘膜染紫色,向外依次为粘膜下层,肌层及外膜.粘膜和部分粘膜下层向肠腔内的突起为半环形皱襞的断面,肌层局部的膨大为结肠带.低倍和高倍观察 (1)粘膜:无绒毛和环形皱襞.由内向外分为三层.
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colon:科隆
科隆(Colon)免税区是拉丁美洲最重要的商业区之一,坐落于千禧年广场(Millennium Plaza)的Four Points by Sheraton 科隆(Colon)酒店是其的一部分,. 在酒店尽享舒适服务,周围是小商品店,饮食区,赌场,旅游中介和汽车租赁机构.
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colon:大肠
扫描报告主要有以下几点内容:首先,肺部的那个小结节和上次的报告相比,没有什么新的发展,算是不错;第二,肝部有些肿大,这应该是由药物所引起的副作用,应该也不是太大的问题;第三,大肠(colon)部位发现有发炎的迹象,麻烦开始有了;
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tandem colon:双点号
...ellipsis 省略号 | ¨tandem colon 双点号 | "ditto 同上
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