blastemal

blastemal的基本解释

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[医]胚基的, 芽基的

与blastemal相关的网络例句 [注：此内容来源于网络，仅供参考]

Wilms tumors with unfaorable histology contain anaplasia – defined as the presence of hyperchromatic, enlarged nuclei (at least 3 times as large as blastemal nuclei), and multipolar mitotic figures.

如有细胞间变则提示Wilms'瘤预后不良，所谓细胞间变，表现为染色质粗糙，胞核增大（至少是后肾胚芽细胞核的3倍大小）以及多极性有丝分裂像。

It also indicates that the expression of WT1 is regulated strictly in time and space, and the aberrant expression of WT1 may result in retarded differentiation of blastemal cell leading NR or nephroblastoma.

提示在散发性肾母细胞瘤发生中除WT1突变外，WT1表达延迟可能是其中起重要作用的机制之一；WT1基因与肾母细胞瘤的组织分化有关，可能诱导胚基细胞向上皮细胞方向分化。

This result indicates that WT1 gene plays an important role in differentiation and development of fetal kidney and may be the factor that promotes metanephric blastemal cell to differentiate into epithelial cell.

结果显示小胎龄肾组织中WT1蛋白在胚基细胞和幼稚肾小球细胞核表达而大胎龄组肾组织中WT1在肾小管细胞胞浆表达，阳性率分别为57.1％(8/14)和46.2%(6/13)，提示WT1基因在胚胎肾分化发育的过程中起着重要作用，WT1蛋白可能是促进后肾胚基细胞向上皮细胞分化的调控因子，其表达在时间上和空间上都受到严格的调控，WT1的表达异常可能导致胚基细胞分化停滞。17例肾母细胞瘤WT1蛋白表达阳性率为41.2%(7/17)，阳性部位在胚基型和上皮型肿瘤细胞核，表达部位和阳性率与早期胚胎肾相似，其中间质型肾母细胞瘤均为阴性，胚基型和上皮型肾母细胞瘤阳性率70%(7/10)，两组间阳性率有显著差异。

Then, under the control of systemic factors, mesenchymal cells aggregate and differentiate to form catilage blastemal elements that prefigure skeletal limb components.

脊椎动物胚胎期骨与关节系统的发生是一种复杂生命现象，起始于中胚层间充质细胞的定向聚集，形成肢芽，然后在一系列作用因子的调控下，肢芽内细胞进一步分化，形成具有骨骼雏形的软骨原基，后者经软骨内骨化发育成骨。

This study demonstrated that WT1 protein was immunohistochemically positive in nuclei of blastemal cells and immature glomerular cells in early fetal kidney, while positive in tubular cytoplasm in late fetal kidney, with the positive percentages 57.1%(8/14) and 46.2%(6/13) respectively.

分别应用WT1蛋白、P53蛋白和CD44V6抗体对27例不同胎龄肾组织和17例不同类型的散发性肾母细胞瘤标本进行免疫组化染色，免疫组化采用Envision两步法。