articular [ɑ:'tikjulə]
- articular的基本解释
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adj.
关节的
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Results 1、 Generally, we can see the original blue and white, shiny, no cracks in the articular surface of the cartilage after the stress increases gradually yellow, surface roughness, cracks appear; when the pressure decreases, the yellowing, rough, the color of the fracture restore gradually and become shiny.2、the shiny smooth surface can be seen under a light microscope, formation, cell distribution, tidy, clear the level of cartilage at the articular surface stress increases, the surface roughness changes, defects, disordered cells, uneven dyeing ; when the articular surface of the pressure gradually decreased, the cartilage gradually repair and the surface of cells at the surface appear only disorder.3、immunohistochemical observation can be seen throughout the observation period, cartilage cells are type Ⅱ collagen expression and expression after 3 weeks gradually weakening, when the seventh week begin to strong gradually.4、 electron microscopy shows that when stress increases the articular surface, the cartilage cells became flat, the cytoplasm in the endoplasmic reticulum, Golgi apparatus decreased with collagen disorders; and when stress decreases the articular surface, cartilage cells gradually returned normal, cytoplasm in the endoplasmic reticulum, Golgi body gradually restore quantity; collagen fibers with a gradual rules.
结果:①大体观察可见到原本蓝白色、有光泽、无裂纹的软骨在关节面压力增大后,逐渐呈灰黄色,表面粗糙,出现裂隙;当压力逐渐减小后,变黄、粗糙、有裂隙的软骨颜色逐渐恢复,变得有光泽②光镜下可见表面光滑、平整,细胞分布均匀、整齐,层次清楚的软骨在关节面压力增大后,表面变粗糙、缺损,细胞排列紊乱、染色不均;当关节面压力逐渐减小后,软骨表面逐渐修复,细胞仅在表层排列紊乱③免疫组织化学观察可见整个观察期内软骨细胞胞浆内均有Ⅱ型胶原表达,术后3周内表达逐渐变弱,从第7周时开始逐渐变强。④电镜下可见当关节面压力增大后,软骨细胞逐渐变扁,胞质中内质网膜、高尔基体减少,胶原排列紊乱;当关节面压力减小,软骨细胞形态逐渐恢复正常,胞质中内质网膜、高尔基体数量逐渐恢复;胶原纤维排列逐渐有规则。
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The human cartilages are composed of chondrocyte and extracellular matrix,the form of chondrocytes are hypertrophy and the quantity are less;the ECM of cartilage are compised of type II collagen and proteoglycan. Articular cartilages are all hyaline with little fibers. Trauma and arthritis are the main cause of cartilage injury,the ommilayer injury ofcartilage can be recovered by marrow,but because of without stimulation mechanism,the new tissues are merely fibrocartilages,they can not be coincide with hyaline cartilage in menchanics;the purely damage of articular cartilage can not stimulate chondrocyte to regenerate because of without blood circulation,thus,the plerosis of articular catilage can not depend on the proliferation of local chondrocyte.Ever since,people tried their best to find a way to reconstruct articular cartilage.
造成人体关节软骨损伤的原因主要为创伤和关节炎,关节软骨全层损伤可由于骨髓中间充质干细胞的高速增殖修复,但这种修复由于缺乏相应的刺激机制,只能形成纤维软骨,而不能形成符合关节生理、力学要求的透明软骨;单纯软骨部分损伤软骨组织内无血管,软骨细胞迁移迟缓,无法使损伤区域软骨细胞再生,因此,关节炎及关节创伤后的软骨修复不能依赖于软骨细胞的增殖和迁移。
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The human cartilages are composed of chondrocyte and extracellular matrix , the form of chondrocytes are hypertrophy and the quantity are less; the ECM of cartilage are compised of type Ⅱ collagen and proteoglycan. Articular cartilages are all hyaline with little fibers. Trauma and arthritis are the main cause of cartilage injury, the ommilayer injury ofcartilage can be recovered by marrow, but because of without stimulation mechanism, the new tissues are merely fibrocartilages, they can not be coincide with hyaline cartilage in menchanics; the purely damage of articular cartilage can not stimulate chondrocyte to regenerate because of without blood circulation, thus, the plerosis of articular catilage can not depend on the proliferation of local chondrocyte. Ever since, people tried their best to find a way to reconstruct articular cartilage.
中文题名人骨髓基质干细胞成软骨诱导及多孔复合材料作为细胞载体的体外实验研究副题名外文题名 Cartilage induction of human mesenchymal stem cells and experiment on compound porous materials as cells' scaffold in vitro 论文作者刘晓岚导师周江南学科专业外科学研究领域\研究方向学位级别博士学位授予单位中南大学学位授予日期2003 论文页码总数68页关键词骨组织工程软骨细胞骨髓基质干细胞壳聚糖高分子外消旋聚乳酸馆藏号BSLW /2003 /R68 /10 造成人体关节软骨损伤的原因主要为创伤和关节炎,关节软骨全层损伤可由于骨髓中间充质干细胞的高速增殖修复,但这种修复由于缺乏相应的刺激机制,只能形成纤维软骨,而不能形成符合关节生理、力学要求的透明软骨;单纯软骨部分损伤软骨组织内无血管,软骨细胞迁移迟缓,无法使损伤区域软骨细胞再生,因此,关节炎及关节创伤后的软骨修复不能依赖于软骨细胞的增殖和迁移。
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articular:关节骨
哺乳类听小骨之一. 由块状的小头和大小3个突起(锤骨柄、长突、短突)所组成. 锤骨柄与短突是在鼓膜的中央与周边部与鼓膜密接,小头以砧锤关节(incudomallear articulation)与砧骨相连接. 与鱼的关节骨(articular)相同.
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articular:关节的
artichoke 朝鲜蓟 | articular 关节的 | articular capsule 关节囊
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articular:关节
关节软骨源性海绵:articular cartilage derived sponge | 关节:articular | 关节内:Intra-articular
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articular:磁共振成像
腕关节盘:Wrist articular disc | 磁共振成像:articular | 骨性关节炎:articular tissue
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articular capsule:关节囊
2.关节囊 关节囊(articular capsule)可分内外两层. 外层纤维排列紧密,与腱和韧带相连处明显增厚;内层较疏松,称为滑膜(synovial membrane). 滑膜内层常被覆2~4层扁平或立方形的上皮样结缔组织细胞,称为滑膜细胞(synovial cell),其基部无基膜,
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