arthritis nodosa
- arthritis nodosa的基本解释
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[医] 变形性关节炎, 关节痛风
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Objectives:Through the detection of the expression level of interleukins-1β(IL-1β), matrix metalloproteinase 9(MMP-9) and nuclear factor kappa B in Synovium and the detection of the concentration of IL-6 and TNF-αin serum of collagen induced arthritis Wister rat, to investigate the relationship between IL-1β、MMP-9、NF-κB and arthritis index in the development of arthritis,and to understand the pathology of synoviocyte.This may provide an experimented proof for the diagnosis of clinical rheumatical arthritis. Methods: Thirty male Wistar rats were randomly divided into two groups,namely the model controlled group and the normal controlled group,three subgroups were randomly divided in model group and controlled group separately.
目的：通过对白细胞介素1β，基质金属蛋白酶-9，转录因子核因子κB在胶原性关节炎大鼠滑膜细胞表达水平的观察，同时监测同期血清细胞因子IL-6和TNF-α的浓度，旨在探讨白细胞介素1β，基质金属蛋白酶-9，转录因子核因子κB与RA发生发展及其与关节指数之间的相关性，了解炎性病变关节滑膜细胞的病理生理状态，进一步为类风湿关节炎的临床治疗提供实验依据。
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Type Ⅱ collagen-induced arthritis in mice,which shares similar characteristics with rheumatoid arthritis,was used as the mode for RA in this study,by taking the incidence,arthritis index,the level of anti-collagenase Ⅱ antibody,the histo-pathological changes as quotas,we observed cantharis plaster's effect on the model by applicating it on acupoints,and measured the splenic interleukin-1 β level of collagen-immunized mice.
采用与类风湿性关节炎特征相似的小鼠胶原诱导性关节炎(Collagen-induced arthritis，CIA)模型，以关节炎发病率、关节炎指数、抗Ⅱ型胶原抗体水平、组织病理学改变等为指标，观察了斑蝥膏穴位敷贴对此模型的影响，并检测了胶原免疫小鼠脾脏白介素-1β水平。
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The time of hight incidence of gout, tuberculosis and traumatic arthritis is from 20 to 40 years old; peak age of rheumatoid arthritis is 40 to 60 years of age; and synovial chondromatosis, osteoarthritis, infectious arthritis lumbar hip disease caused the incidence of knee pain increases with age increased.
3痛风、结核及创伤性关节炎的高发年龄为20～40岁，类风湿性关节炎的高峰年龄为40～60岁，滑膜软骨瘤、骨性关节炎、感染性关节炎及腰髋部疾病造成膝关节疼痛的发病率随年龄的增长而升高。
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nodosa periarteritis：结节状动脉周围炎
\\"结节状\\",\\"nodosa\\" | \\"结节状动脉周围炎\\",\\"nodosa periarteritis\\" | \\"结节状多动脉炎\\",\\"nodosa polyarteritis\\"
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gouty arthritis：痛风
治疗:gouty arthritis | 痛风:Gouty-arthritis | 关节炎:Arthritis
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traumatic arthritis of subastragalar joint：距下关节损伤性关节炎,距下关节损伤性关节炎
traumatic arthritis of knee joint 膝关... | traumatic arthritis of subastragalar joint 距下关节损伤性关节炎,距下关节损伤性关节炎 | traumatic arthritis of talonavicular joint 距舟关节创伤性关...