apomorphine [,æpəu'mɔ:fi:n]
- apomorphine的基本解释
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阿扑吗啡, 阿朴吗啡, 脱水吗啡
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After a two-week screening period, 18 patients participated in a four-week as-required regimen of 2 mg apomorphine SL, escalated to 3 mg when appropriate after two weeks. Three patients (16.7%) benefited from this treatment modality ( P .05). The nonresponding group of 15 patients continued with a daily regimen of 2 mg apomorphine SL for two weeks followed by 3 mg daily for two weeks. The 3 mg daily regimen was more effective for ED ( P .02) and for each sexual domain scored with the International Index of Erectile Function questionnaire. Adverse events, as reported by three patients (23%) during the 3 mg regimen, were nausea, dizziness, and headache.
在二星期的筛检过程之后,18位病患参与为期四个星期的2mg,在两星期后适当的增加至3mg的阿朴吗啡 SL疗法,其中三位病患(16.7%)受益于这种治疗方法(P 。05),15位无反应的病患持续接受每日2 mg的阿朴吗啡 SL两周后,再接著以每日3 mg的两周治疗,对于ED及国际勃起功能指数调查表的每项性功能区计分,每日3 mg的疗法比较有效(P 。02),在接受3 mg疗法期间三位病患( 23%)的不良事件,为恶心、眩晕、和头痛。
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At baseline and on day 1, 3, 7, 14, 21 following MPP+ injection, the degree of microglial activation was examined by detecting the immunodensity of OX-42 in the substantia nigra. The number of viable dopaminergic neurons was determined by measuring tyrosine hydroxylase positive neurons in the SN. Behavioral performances were evaluated by counting the number of rotations induced by apomorphine, calculating scores of forelimb akinesia and vibrissae-elicited forelimb placing asymmetry.
分别在基线、MPP+注射后第1、3、7、14、21天时通过测定黑质区域OX-42的免疫荧光强度评定小胶质细胞的激活程度,测定酪氨酸羟化酶的表达情况评定存活多巴胺神经元的数量;通过阿朴吗啡诱导的旋转行为、前肢跨步及触须引发的不对称放置试验得分测评行为学表现。
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The rats were tested for rotational behavior induced by apomorphine for 40 min every week.
用小动脉旋转行为监测仪记录Apomorphine诱发的大鼠异常旋转行为、脑组织液生化和组织形态的变化。
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apomorphine:阿扑吗啡
3 多巴胺受体激动剂 阿扑吗啡(Apomorphine)是D1/D2受体激动剂,目前认为阿扑吗啡诱导勃起是通过骶副交感神经丛扩张阴茎海绵体动脉引起. 以往的观点是阿扑吗啡几乎对不同程度的ED病人都有效,但是最近Maclennan等[25]在英国做的一项随机临床试验(RCT)研究(11185例,
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apomorphine:阿朴吗啡
1.1.1 阿朴吗啡(apomorphine) 是吗啡的衍生物,属于D2型多巴胺受体激动药,主要作用于下丘脑性活动中枢,启动和调节勃起功能. 剂量因人而异,每次用量2,4,5,6 mg,有效率分别为44.0%,58.1%,52.8%,60.9%. 不良反应有轻度恶心、呕吐.
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apomorphine:脱水吗啡
apology 辩护 | apomorphine 脱水吗啡 | aponia 无痛
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apomorphine:阿扑吗啡[催吐药]
Apicycline 阿哌环素[抗生素类药] | Apomorphine 阿扑吗啡[催吐药] | Apovincamine 阿扑长春胺[血管扩张药]
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APOMORPHINE HCL:烟酸阿朴吗啡
烟酸 Nicotinic Acid | 烟酸阿朴吗啡 APOMORPHINE HCL | 烟酸胺 niacinamide usp
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