agonist ['ægənist]

agonist的基本解释

n.

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与agonist相关的网络例句 [注：此内容来源于网络，仅供参考]

Intravoneous injection of 0.5mg/kgBW jingsongling cause the 60 minutesrelaxation of goat gastric motor.The effects of jingsongling on the gastric motor ofgoat is major of effects of α2 -adrenoceptor agonist,as well as that of α1 -adrenoceptor agonist,the effects of α1 -adrenoceptor agonist concentrate at thecardic and pylorus;the function of α2 -adrenoceptor exit widely at cardic,pylorus,rumen,reticulum,omasum and abomasum,the function at different part is not the same.The lowestdose of jingsonglinginhibiting the amplitude and frequency of the gastricmyoelectric is 0.01mg/kgBW;the influence of jingsonglingto the gastricmotility of goat is dose-dependent,and the amplitude regain after the frequency ofgastric myoelectriv wave.When the goat revived,the gastric motor function is notreach the level of the normal;the major reason ofjingsongling cause the goat gastricrelaxation is the amplitude renew slowly.The intravoneous injection ofjingsonglingfirst,after 5 minutes,intravoneous injection the antagonist,the effect of prazosin and idazoxan mixed is best,which can fast reversal of theinhibition of jingsongling on the gastric motor of goat,the effects of idazoxan isgood,and the prazosin block the effection of jingsongling is better than that ofxylazine,especially at cardia and pylorus.When intravoneous injection of0.5mg/kgBW idazoxan and/or prazosin only,the amplitude of gastric myoelectric ingoat increases at a certain degree,but the frequency is not changed.

静脉注射0.5mk/kgBW的静松灵引起山羊胃蠕动弛缓长达60分钟；静脉注射0.5mg/kgBW的静松灵对山羊胃蠕动机能的影响是以α2肾上腺素受体作用为主的，兼有α1肾上腺素受体的作用，而且静松灵的α1肾上腺素受体的作用主要集中在幽门和贲门；α2肾上腺素受体的作用广泛存在于贲门、瘤胃、网胃、瓣胃、皱胃和幽门中，不同部位间有功能上的差异；静注0.01mg/kgBW的静松灵是对山羊的贲门、瘤胃、网胃、瓣胃、皱胃和幽门的肌电波频率和振幅均产生影响的最低剂量；静注一定剂量的静松灵对山羊胃蠕动的抑制作用与剂量呈相关性；而且山羊胃肌电波振幅的恢复比肌电波频率的恢复慢；苏醒时山羊的胃蠕动机能尚未恢复到正常状态；静松灵引起山羊胃弛缓的主要原因是由于胃肌电波的振幅恢复慢；静注0.5mg/kgBW的静松灵，5分钟后静注0.5mg/kgBW的拮抗剂时，咪唑克生+哌唑嗪的作用最好，能迅速地逆转静松灵对山羊胃蠕动的抑制作用，咪唑克生也有很强的拮抗作用，而哌唑嗪对静松灵的拮抗效果好于对隆朋的拮抗；单独静注0.5mg/kgBW的咪唑克生和/或哌唑嗪时，山羊的瘤胃、网胃、瓣胃、皱胃、贲门和幽门的肌电波振幅有一定程度的增强，而肌电波频率未见变化。

The affected chicks acquired the morphine conditioned place preference more quickly, and maintained it much longer. Experiment 3 showed that during E5-8, injecting delta receptor antagonist naltrindole reversed the learning and memory impairment caused by morphine while delta receptor agonist DPDPE impaired learning and partial memory function. On the other hand, mu opioid receptors had little effect. As for E17-20, given naloxonazine can reverse the increases of susceptibility to morphine, and the mu receptor agonist DAGO cause the increases of susceptibility to morphine. Delta receptors have no effect.

研究结果发现：经过对鸡胚发育不同时间段的吗啡给药，胚胎期发育E5-8阶段给予吗啡的小鸡学习记忆受损最为严重，表现为学习和记忆功能的严重下降；而E17-20时段吗啡给药的小鸡更容易获得吗啡CPP且保持时间更长。E5-8阶段给予delta受体拮抗剂natrindole能够翻转吗啡对学习和记忆的损害作用，并且给予delta受体激动剂DPDPE也损害学习和部分记忆功能，mu受体作用不大。E17-20阶段拮抗mu受体能够抑制成瘾易感性的增加，激动mu受体可以增加小鸡的成瘾易感性，delta受体没有明显作用。

Furthermore, agonist induced internalization of DOR, but KOR failed to be internalized after agonist stimulation.

而在共转GRK2和GRK5质粒的细胞中，在U69593或Dynorphin A的刺激后，未观察到KOR的磷酸化。

与agonist相关的网络解释 [注：此内容来源于网络，仅供参考]

agonist：激动剂

分子结构变化后生物活性增强的激素类似物,称为激动剂(agonist),如促排2号、苯甲酸雌二醇的生物活性分别比促性腺激素释放激素(GnRH)和雌二醇高,因此分别是这两种激素的激动剂.

agonist：兴奋剂

动力学测定显示人体内的NMDA1A/2D对谷氨酸和甘氨酸有很高亲和力的原因可能是由于1A/2D的兴奋剂(agonist)解离较慢. 该亚型1A/2D显示为一种具有特殊药理功能的受体并能构成一种重要的活化因子. 另外,

agonist：主动肌

临床观察所得不良姿势往往会使身体局部出现肌肉不平衡(Muscle Imbalance),即一部分肌肉过紧,而其他部分肌肉倾向于软弱无力,这会在主动肌(Agonist)和拮抗肌(Antagonist)之间产生不平衡,肌肉不平衡通常出现于对角(Diagonal Pattern):缩短/过紧或软弱无力/拉

agonist：促效剂

2型糖尿病患者表现出相对的 GIP 抵抗,而对 GLP-1R 促效剂(agonist)则无. 现就GLP-1和其类似物的生物学特征及其近年来在2型糖尿病治疗中的研究作一概述. 一、GLP-1的生物学特征及病理生理作用1.GLP-1的基因和结构:人类胰高血糖素原基因位于染作者:刁红梅;

acetylcholine agonist：乙酰胆碱拮抗剂

acetylcholine乙酰胆碱 | acetylcholine agonist乙酰胆碱拮抗剂 | acetylcholine receptor乙酰胆碱受体