SARS
- SARS的基本解释
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abbr.
Severe Acute Respiratory Syndrome 严重急性呼吸道综合征, 俗称非典型肺炎
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Methods A nested RT-PCR was used for detecting one fragment of SARS-CoV RNA in oropharyngeal swabs from 3 SARS probable patients ,4 SARS suspect patients and other 27 patients with fever in Hangzhou, and the nested RT-PCR product from one SARS probable patient was sequenced.Meanwhile in these 3 SARS probable patients, other three RT-PCR methods, including a hemi -nested RT-PCR targeted for another fragment of SARS-CoV RNA, a real-time RT -PCR and a modified nested real-time RT-PCR, were employed to detect SARS-Co V RNA.Results Two positives were found in the 3 SARS pro bable patients, and none positive in 4 SARS suspect patients and other 27 patien ts with fever, using the nested RT-PCR.
方法对2003年杭州市3例严重急性呼吸综合征临床确诊患者、4例疑似和27名医学观察者的咽拭子标本用巢式实时RT-PCR检测SARS-CoV核酸,对阳性扩增产物进行核酸序列测定,同时对3例患者的标本应用半巢式RT-PCR检测另一位点SARS-CoV核酸片段,并应用常规实时RT-PCR技术及改良实时RT-PCR技术进行检测。
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Methods: We analyzed nucleic acid sequence of the SARS-CoV and SARS-like CoV which were obtained from the GeneBank. The evolutionary trees of SARS-CoV and SARS-like CoV were made up by using the Brede virus as outgroup, and analyzed variation in single nucleotide sequence.
对GenBank登录的SARS冠状病毒和SARS样冠状病毒(SARS-like CoV)核酸序列进行了分析,以Breda病毒为外组,构建了SARS冠状病毒和SARS样冠状病毒系统进化树,并进行单核苷酸变异分析。
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Nucleoprotein is also a major immunogenetic antigen for SARS; however, several tests have shown that N protein had the reactivity with other coronavirus positive sera. It is therefore an advantage of S protein as recombinant target antigen for SARS serum diagnosis compared with recombinant N protein. Moreover, S protein has been shown to be the major antigenic determinant that induces neutralizing antibodies and protective immunity to SARS-CoV, so it is also important in designing SARS genetic engineering vaccine.
SARS-CoV S 蛋白由1255 个氨基酸组成,体外表达如此大的蛋白很困难,而且表达蛋白的可溶性不高;其次,实验已经证实,全长S 蛋白含有大量无关的表位,致使表达的全长S蛋白对SARS 阳性血清的检出率低于S 蛋白片段;另外作为疫苗研究,S 蛋白上大量无关表位作为异体蛋白进入体内,会引发机体的过度免疫反应,这也是SARS-CoV 可能的致病机理之一。
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SARS:非典
从此可以一心一意只为中国自己谋利益而无需再婆婆妈妈地 瞻前顾后. 所有这些都是在这次"非典"(SARS)爆发之前发生的事,是许多中国人把新加 坡当亲戚朋友、关键时刻挺身而出帮人渡过难关时发生的事. 当中国遭受"非典 "(SARS)灾害之际,新加坡又做了些什么?
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SARS:非典型性肺炎
>消息,日本官房副长官上野公成在今天上午举行的记者招待会上表示,日本目前被怀疑感染上"非典型性肺炎"(SARS)的人数已经上升至57人.
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SARS:非典型肺炎
禽流感应急处理预案................(4)2.福清局突发公共卫生事件应急预案...........................(10)3.福清检验检疫局口岸食物中毒应急处理预案..............(15)4.福清检验检疫局\"非典型肺炎\"(SARS)应急处理预案
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SARS:严重急性呼吸综合征
进入2003年,这一后来被称为"严重急性呼吸综合征"(SARS)的传染病,开始向全国和世界其他地方蔓延. 突如其来的SARS疫情引起的恐慌和影响,更远远超过了SARS本身. SARS不仅给人们的健康和生命带来严重的威胁,而且对社会稳定和经济发展造成巨大影响.
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SARS:abbr. svere acute respiratory syndrome; 严重急性呼吸综合征
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