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Material and MethodsRA Rabbit Model group: 15 early RA rabbits of the same weight and variety Control group:10 normal rabbits of the same weight and varietyMethods of making RA rabbit model:elect 15 normal rabbits of the same weight and variety, dissolve Ovalbumin in 0.9% sodium chloride solution, to make the solution of 20mg/ml concengtration, blend the same quantity of complete Freund′s Adjuvant equably ,inject the mixed solution into endermic tissue of the rabbit′s scapular section, making the rabbits allergic, inject 1 ml of the mixed solution to one rabbit every time, inject 1 ml of the mixed solution in 5 different places of the rabbit′s scapular section, inject the rabbit one time every week,inject 3 weeks continuously,it turned out to be that the rabbits will be allergic, inject Ovalbumin blent with the 0.9% sodium chloride solution into the knee joint cavity of the rabbits in the fourth week, 5 mg Ovalbumin every knee joint cavity,two knees of every rabbit of the 15 rabbits are both injected,the arthrosis diameter and the exterior temperature of the knees will be added obviously in 24 hours,and they will drop gradually,at the time of the 14th or 21th day, the arthrosis diameter and the exterior temperature of the knees will get to the balance time,the incidence rate of RA is 100%.after the RA model succeeds,it is the early time of RA from the first week to the fourth week,after the fourth week,it is the late time of RA, the cartilage of the femoral condyle and the subchondral bone cortices will be changed unrecoverily.
资料与方法RA模型组:早期RA家兔模型15只,品种及体重接近。对照组:正常家兔10只,品种及体重接近。RA家兔模型制作方法:选取15只成年家兔,体重、品种接近,将卵蛋白溶解于生理盐水,配成浓度为20mg/ml的溶液,与等量完全弗氏佐剂混匀,注入家兔肩胛区皮下致敏,每只家兔每次注射1ml,于肩胛区5个不同区域注射,每周一次,连续注射3周而致敏,第4周向膝关节腔注射卵蛋白生理盐水溶液,每只关节腔注射5mg卵蛋白,15只家兔膝关节全部注射,24h内此关节直径和表面温度大幅度上升,以后缓慢下降,至14~21d达到平台期,发病率达100%。造模成功后第1~4周为早期改变,第4周以后出现不可逆的关节软骨及骨破坏。采用高频超声对RA模型组与对照组的膝关节髌上囊液体厚度、滑膜及股骨髁软骨厚度及软骨下骨皮质的回声情况进行对比观察。结果RA组模型组膝关节髌上囊积液及滑膜的厚度明显厚于对照组,其股骨髁软骨的厚度与对照组相比无明显差异,其软骨下骨皮质与对照组相比无明显改变。
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PLT and PCT of RA patients in active phase were increased, and have correlation with reactive indexes. It suggests that PLT, PCT can reflect reactiveness of RA as objective indexes. XFC can not only treat inflammation and delay the aggravation of RA patient by improving platelet ultrastructure.
活动期RA患者PLT、PCT显著升高,且与各活动性指标具有相关性,提示PLT、PCT可作为反映RA活动性的客观指标;新风胶囊能通过改善血小板超微结构从而减少CD62P释放来改善RA患者的关节炎症病变,延缓病情进展。
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Expect for a few pittings,the N+1-implanted surface had a best fineness (average roughness Ra≈4.2nm), close to the unimplanted original surface.The N+2-implanted surface had a black dendritic area,and had a poorer fineness (Ra≈16nm).While in the N+10-implanted surface appeared a ripple structure,with the poorest fineness (Ra≈40nm).
但其表面形貌各异:N+1注入的表面除存在少量点蚀坑外,光洁度最高(平均粗糙度Ra≈4.2nm),接近未注入前的原始表面(Ra≈3.5nm);N+2注入的出现黑色枝状区域,光洁度次之(Ra≈16nm),而N+10注入的则出现&波纹&状结构,光洁度最差(Ra≈40nm)。
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RA Radio Astronomy:射电天文学
RA Radio Astronomy 射电天文学 | RA Random Access 随机存取 | RA Rate Adaptation 速率索赔
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a'unga'ra:同aunga'ra,其義為煤炭,木炭
a'unga'r:"火"的意思,也代表煤炭 | a'unga'ra:同aunga'ra,其義為煤炭,木炭 | a'unga'rd'iha:有火的地方(又指內有煤炭的地方)
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contador,ra:会计
校长:director,ra; rector,ra | 会计:contador,ra | 厨师:cocinero,ra